In another post, I have uploaded and documented a minirt init modification handling cloop and squashfs transparently for the user, just using cheatcode "squashfs". It's for pure 64-bits, but the modification for 32-bits is trivial.
IMHO, present day squashfs seems to be about as stable, efficient and versatile as we need for this kind of use, and its widespread and growing use indicates others think the same.
So, with a "uni-minirt", KNOPPIX may still be distributed as cloop image, but subsequent remasterings will not have to unpack minirt.gz to make modifications in order to turn to squashfs. I think lots of remasterers will prefer squashfs, as it gives (at least) slightly simpler and faster workflow with at least as good results. OTOH. I can't see anything right now forcing us to use squashfs.
And, just for the record: This is not about the practicality or usability of cloop per se, but about the actual Knoppix use case.
Z80 - NABU PC & Keyboard - Vintage New Old Stock (Retro 80's)
$139.99
$33.00
Z80 - NABU PC & Keyboard - (With Issues) Vintage NOS (Retro 80's)
$99.99
Vintage Apple IIe French / Français Manual & Introduction Disk
$22.00
(2) - Vintage Rare Intel i960 A80960CA33 Processor Collection or Gold Recovery
$34.77
Vintage Paradyne Gte Telenet T-96
$160.00
BlueSCSI V2 WiFi (Desktop) Modern Storage for Vintage Computers Latest Model
$53.50
NEW Manufacture OLD STYLE Oval 3 Prong Power Cord HP style 125V 7A 875W Vintage
$39.95
DATAPOINT vintage PRINTER EXTREMELY clean MICROLINE 92 MADE IN JAPAN
$249.00
Vintage Comfort Keyboard Systems Ergomagic Mechanical AT/PS2 Keyboard
$119.99